Oxonica Diagnostics

Optical Properties & Benefits

Nanoplex™ biotags are optical detection nanoparticles with ideal characteristic for a wide range of Clinical and Life Science applications.

  • Patented technology leverages the performance of surface enhanced Rarr an scattering (SERS)
  • Convenient, glass encapsulated format which allows for simple biofunctionalization with proteins and nucleic acids
  • Particles are inert and uniform in size
  • SERS signal is photostable and, unlike fluorescence, cannot be “quenched”
  • Signal is unaffected by ionic strength or temperature variations and is resistant to matrix interference
  • Exploiting the low background interference of near-IR detection (785 nm) allows for data collection in whole blood and other biological matrices
  • Multiplexed detection capabilities
  • Proprietary software for spectral deconvolution and signal analysis
Nanoplex™ biotags Composition

Gold core

Adsorbed reporter molecule with known
characteristic Raman spectrum. Multiple unique
reporters available.

Silica encapsulation

schema of biological recognition molecules

Composite spectra of mixture of three different
tags as measured in a multiplexed assay

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Proprietary software quantitatively
deconvolutes spectra of each tag

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Software reports amount of each tag
present in sample